Beliaeva N N, Bonashevskaia T I, Marshak T L, Brodskiĭ V Ia
Biull Eksp Biol Med. 1977 Mar;83(3):345-8.
The cytophotometric and kariometric study of the liver hepatocytes in albino rats inhalationally exposed to dichlor- and trichlorpropan showed the latter to be more toxic than the former by its effect on the polyploidization of hepatocyte nuclei. The development of polyploidization was determined by the concentration level of the active agent and the length of exposure to it: the lower the concentration--the more time was required for the realization of the effect.
对白化大鼠吸入二氯丙烷和三氯丙烷后肝脏肝细胞进行的细胞光度学和核测量学研究表明，就对肝细胞核多倍体化的影响而言，三氯丙烷比二氯丙烷毒性更大。多倍体化的发展取决于活性剂的浓度水平及其暴露时间：浓度越低，实现该效应所需的时间就越长。
