Tritapepe R, Di Padova C, Rovagnati P
Experientia. 1980 May 15;36(5):580-1. doi: 10.1007/BF01965813.
The spontaneous reversal ethinyl estradiol-induced cholestasis has been documented 7 days after the last estrogen administration in the rat. This finding supports the hypothesis that estrogens produce only a transient functional failure of the hepatocytic structures responsible for bile secretion.
在大鼠中,已记录到末次给予雌激素后7天,乙炔雌二醇诱导的胆汁淤积会自发逆转。这一发现支持了以下假说:雌激素只会导致负责胆汁分泌的肝细胞结构出现短暂的功能衰竭。