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[西盖丁治疗因子宫胎盘血液循环减少导致的兔产前个体发育中的发育障碍]

[Sigetin treatment of the developmental disorders induced in rabbit prenatal ontogeny by curtailment of the uteroplacental blood circulation].

作者信息

Antonov V V

出版信息

Farmakol Toksikol. 1980 Jan-Feb;43(1):59-62.

PMID:7379993
Abstract

About 40 per cent of the uterine preplacental vessels were ligated in rabbits on the 11th or 18th days of gestation. Some of the female rabbits operated upon were given 5 mg of intravenous sigetin twice a day till the end of pregnancy. Investigation of the progeny development, the ability of learning at an age of about 6 months, in particular, showed a somewhat better development and ability of learning in the offsprings of female rabbits receiving sigetin.

摘要

在妊娠第11天或第18天对家兔结扎约40%的胎盘前置子宫血管。部分接受手术的雌兔每天静脉注射5毫克西盖汀,直至妊娠结束。对后代发育的研究,特别是对约6个月龄时学习能力的研究表明,接受西盖汀的雌兔后代的发育和学习能力略好一些。

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