Kela A K, Reddy L P, Thombre D P
Indian J Physiol Pharmacol. 1980 Apr-Jun;24(2):84-90.
Electrocardiograms of normal rats were studied and compared with those of the rats receiving parenteral IPT. The rat E.C.G. resembles essentially human E.C.G. IPT administration brought about E.C.G. changes suggesting myocardial infarction. Appearance of Q wave in aVL was a consistent feature of E.C.G. after 24 hr of IPT injection. With additional doses of IPT the ECG in these rats showed a well marked Q wave and increase in the amplitudes of R and T waves in limb and increase in the amplitudes of R and T waves in limb and chest leads.
对正常大鼠的心电图进行了研究，并与接受肠外异丙嗪治疗的大鼠的心电图进行了比较。大鼠心电图与人类心电图基本相似。给予异丙嗪导致心电图改变，提示心肌梗死。注射异丙嗪24小时后，aVL导联出现Q波是心电图的一个一致特征。给予额外剂量的异丙嗪后，这些大鼠的心电图显示出明显的Q波，肢体导联R波和T波振幅增加，胸导联R波和T波振幅也增加。
