来自患有克林霉素相关性结肠炎的豚鼠的盲肠毒素，被索氏梭菌抗毒素中和。
Cecal toxin(s) from guinea pigs with clindamycin-associated colitis, neutralized by Clostridium sordellii antitoxin.
作者信息
Rehg J E
出版信息
Infect Immun. 1980 Feb;27(2):387-90. doi: 10.1128/iai.27.2.387-390.1980.
Abstract
The cecal contents of guinea pigs with clindamycin-associated colitis contained a heat-labile toxin. This toxin was lethal for guinea pigs and mice, produced vascular permeability in the skin of rabbits, and was cytotoxic in tissue culture. The lethality in mice, vascular permeability in rabbit skin, and cytotoxicity in tissue culture monolayers were neutralized by Clostridium sordellii antitoxin.
摘要
患有克林霉素相关性结肠炎的豚鼠盲肠内容物中含有一种热不稳定毒素。这种毒素对豚鼠和小鼠具有致死性，可使兔皮肤血管通透性增加，并且在组织培养中具有细胞毒性。小鼠的致死性、兔皮肤的血管通透性以及组织培养单层中的细胞毒性均被索氏梭菌抗毒素中和。
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