Chemotherapeutic management of transmissible venereal tumors in 30 dogs.

Thirty dogs with transmissible venereal tumors were examined either at The Donaldson-Atwood Cancer Clinic of The Animal Medical Center or at The University of Georgia Veterinary Medical Teaching Hospital. After biopsy, all dogs were treated with a combination chemotherapy regimen consisting of vincristine, cyclophosphamide, and methotrexate. Results of therapy were evaluated after a mean interval of 533 days; 28 had complete regression of tumor, 1 had a partial response, and 1 had a minimal response.