FR-900130，一种新型氨基酸抗生素。II. FR-900130乙酰衍生物的分离与结构解析

FR-900130, a novel amino acid antibiotic. II. Isolation and structure elucidation of the acetyl derivative of FR-900130.

作者信息

Kuroda Y, Okuhara M, Goto T, Kohsaka M, Aoki H, Imanaka H

出版信息

J Antibiot (Tokyo). 1980 Feb;33(2):132-6. doi: 10.7164/antibiotics.33.132.

DOI:10.7164/antibiotics.33.132

Abstract

FR-900130 is a new antibiotic having an acetylene moiety and is very unstable in aqueous solution. The antibiotic was isolated as the acetyl derivative by ion-exchange resin and adsorption chromatography. The structure has been determined to be L-2-amino-3-butynoic acid by spectral data of its derivatives.

摘要

FR - 900130是一种具有乙炔部分的新型抗生素，在水溶液中非常不稳定。该抗生素通过离子交换树脂和吸附色谱法分离为乙酰衍生物。通过其衍生物的光谱数据确定其结构为L - 2 - 氨基 - 3 - 丁炔酸。