• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

The structure of manumycin. II. Derivatives.

作者信息

Zeeck A, Frobel K, Heusel C, Schröder K, Thiericke R

机构信息

Institut für Organische Chemie, Universität Göttingen, FRG.

出版信息

J Antibiot (Tokyo). 1987 Nov;40(11):1541-8. doi: 10.7164/antibiotics.40.1541.

DOI:10.7164/antibiotics.40.1541
PMID:3693124
Abstract

Derivatives of manumycin (1) were obtained by acetylation and reduction, respectively, and characterized by their spectroscopic data. Structure-activity relationships of the antibiotic were discussed.

摘要

相似文献

1
The structure of manumycin. II. Derivatives.
J Antibiot (Tokyo). 1987 Nov;40(11):1541-8. doi: 10.7164/antibiotics.40.1541.
2
The structure of manumycin. I. Characterization, structure elucidation and biological activity.曼诺霉素的结构。I. 表征、结构解析及生物活性。
J Antibiot (Tokyo). 1987 Nov;40(11):1530-40. doi: 10.7164/antibiotics.40.1530.
3
The structure of manumycin. III. Absolute configuration and conformational studies.曼诺霉素的结构。III. 绝对构型和构象研究。
J Antibiot (Tokyo). 1987 Nov;40(11):1549-54. doi: 10.7164/antibiotics.40.1549.
4
Biosynthesis of manumycin: origin of the polyene chains.
J Antibiot (Tokyo). 1988 May;41(5):694-6. doi: 10.7164/antibiotics.41.694.
5
[METABOLITES OF MICROORGANISMS. 41. MANUMYCIN].
Pharm Acta Helv. 1963 Dec;38:871-4.
6
The manumycin-group metabolites.
Nat Prod Rep. 1998 Jun;15(3):221-40. doi: 10.1039/a815221y.
7
Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106. II. Structure determination and structure-activity relationships.尼沙霉素，一种来自链霉菌属K106的新型马尼霉素类抗生素。II. 结构测定及构效关系
J Antibiot (Tokyo). 1994 Oct;47(10):1110-5. doi: 10.7164/antibiotics.47.1110.
8
FR-900130, a novel amino acid antibiotic. II. Isolation and structure elucidation of the acetyl derivative of FR-900130.FR-900130，一种新型氨基酸抗生素。II. FR-900130乙酰衍生物的分离与结构解析
J Antibiot (Tokyo). 1980 Feb;33(2):132-6. doi: 10.7164/antibiotics.33.132.
9
Nocardicin A, a new monocyclic beta-lactam antibiotic II. Structure determination of nocardicins A and B.
J Antibiot (Tokyo). 1976 Sep;29(9):890-901. doi: 10.7164/antibiotics.29.890.
10
Manumycin A downregulates release of proinflammatory cytokines from TNF alpha stimulated human monocytes.曼诺霉素A可下调肿瘤坏死因子α刺激的人单核细胞中促炎细胞因子的释放。
Immunol Lett. 2016 Jan;169:8-14. doi: 10.1016/j.imlet.2015.11.010. Epub 2015 Nov 18.

引用本文的文献

1
Identification of Antimicrobial Compounds in Two sp. Strains Isolated From Beehives.从蜂箱中分离出的两种菌株中抗菌化合物的鉴定。
Front Microbiol. 2022 Feb 3;13:742168. doi: 10.3389/fmicb.2022.742168. eCollection 2022.
2
Bacteria Are New Targets for Inhibitors of Human Farnesyltransferase.细菌是人类法尼基转移酶抑制剂的新靶点。
Front Microbiol. 2021 Nov 30;12:628283. doi: 10.3389/fmicb.2021.628283. eCollection 2021.
3
Activation of a Cryptic Manumycin-Type Biosynthetic Gene Cluster of DSM44229 by Series of Genetic Manipulations.
通过一系列基因操作激活DSM44229中一个隐秘的曼诺霉素型生物合成基因簇
Microorganisms. 2021 Mar 8;9(3):559. doi: 10.3390/microorganisms9030559.
4
Inhibition of Pro-Inflammatory Cytokines by Metabolites of Streptomycetes-A Potential Alternative to Current Anti-Inflammatory Drugs?链霉菌代谢产物对促炎细胞因子的抑制作用——当前抗炎药物的潜在替代品？
Microorganisms. 2020 Apr 25;8(5):621. doi: 10.3390/microorganisms8050621.
5
Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp.Carpatamides A-C，来自海洋来源的链霉菌属的细胞毒性芳基胺衍生物。
J Nat Prod. 2014 May 23;77(5):1245-8. doi: 10.1021/np500207p. Epub 2014 Apr 23.
6
Hyaluromycin, a new hyaluronidase inhibitor of polyketide origin from marine Streptomyces sp.透明质霉素，一种源自海洋链霉菌属的新型聚酮类透明质酸酶抑制剂
Mar Drugs. 2014 Jan 21;12(1):491-507. doi: 10.3390/md12010491.
7
Identification of Ras farnesyltransferase inhibitors by microbial screening.通过微生物筛选鉴定Ras法尼基转移酶抑制剂
Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2281-5. doi: 10.1073/pnas.90.6.2281.