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通过高效液相色谱法对异构可卡因进行阳性鉴定和定量分析。

Positive identification and quantitation of isomeric cocaines by high-performance liquid chromatography.

作者信息

Lewin A H, Parker S R, Carroll F I

出版信息

J Chromatogr. 1980 May 30;193(3):371-80. doi: 10.1016/s0021-9673(00)87737-7.

DOI:10.1016/s0021-9673(00)87737-7
PMID:7380965
Abstract

A high-performance liquid chromatographic procedure for separating and identifying the four isomeric cocaines has been developed. Use of this procedure with an internal standard allows for the determination of the quantity of any isomeric cocaine in an unknown sample. The pitfalls and problems encountered in the use of gas chromatography and mass spectrometry in the analysis of cocaines and ecgonine methyl esters are discussed.

摘要

已开发出一种用于分离和鉴定四种可卡因异构体的高效液相色谱方法。将该方法与内标物一起使用,可以测定未知样品中任何可卡因异构体的含量。文中讨论了在可卡因和芽子碱甲酯分析中使用气相色谱法和质谱法时遇到的陷阱和问题。

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2
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