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Determination of cocaine in human hair by gas chromatography/mass spectrometry.

作者信息

Balabanova S, Homoki J

机构信息

Department of Forensic Medicine, University of Ulm, Federal Republic of Germany.

出版信息

Z Rechtsmed. 1987;98(4):235-40. doi: 10.1007/BF00201228.

DOI:10.1007/BF00201228
PMID:3660952
Abstract

A qualitative method for the determination of cocaine alone without its metabolites in human hair by gas chromatography/mass spectrometry (GC/MS) was developed. The assay used helium as carrier gas, a 30-m bonded phase fused silica OV-1 capillary column, and solid injection at 290 degrees C evaporator temperature. The cocaine concentrations in hair were determined also by radioimmunoassay (RIA). The values obtained are the sum of cocaine and its metabolites. Both GC/MS and RIA meet the requirements for the determination of drug abuse by two different methods in forensic science.

摘要

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本文引用的文献

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Distribution and metabolism of cocaine in the dog and rabbit.可卡因在犬和兔体内的分布与代谢。
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The determination of cocaine and its major metabolite, benzoylecgonine, in postmortem fluids and tissues by computerized gas chromatography/mass spectrometry.采用计算机化气相色谱/质谱法测定死后体液和组织中的可卡因及其主要代谢物苯甲酰爱康宁。
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