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约旦的白喉:一种虽在减少但仍很重要的儿科疾病。

Diphtheria in Jordan: a diminishing yet important paediatric disease.

作者信息

Khuri-Bulos N

出版信息

J Trop Med Hyg. 1980 Apr;83(2):79-83.

PMID:7381985
Abstract

Twenty-seven cases of diphtheria (15 male, 12 female) admitted over a 2-year period, 1977-1978, at the Jordan University Hospital were reviewed. The majority were admitted during autumn and were in the 2-9-year age group. Eleven patients were not vaccinated and six were questionably vaccinated; of these seven died. In 10 patients who were partially or completely vaccinated, only one died. Antitoxin was given to 23 patients at varying intervals after the onset of the disease. No antitoxin was given to the patients who were admitted after the tenth day of the illness. Fourteen complications developed in 13 patients. One patient died with upper airway obstruction, four died with myocarditis, and three patients died with the respiratory complications of polyneuritis. The case fatality rate was 29%. While in Jordan the incidence rate of diphtheria has been decreasing steadily, limited outbreaks are likely to continue to occur unless a higher immunization rate is achieved.

摘要

对1977年至1978年这两年间约旦大学医院收治的27例白喉病例(15例男性,12例女性)进行了回顾性研究。大多数病例在秋季入院,年龄在2至9岁之间。11例患者未接种疫苗,6例接种情况存疑;其中7例死亡。在10例部分或完全接种疫苗的患者中,仅1例死亡。23例患者在发病后不同时间间隔接受了抗毒素治疗。发病第十天后入院的患者未接受抗毒素治疗。13例患者出现了14种并发症。1例患者死于上呼吸道梗阻,4例死于心肌炎,3例患者死于多发性神经炎的呼吸并发症。病死率为29%。虽然约旦白喉发病率一直在稳步下降,但除非实现更高的免疫接种率,否则可能会继续出现局部疫情。

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引用本文的文献

1
Prognosis in patients with diphtheric myocarditis and bradyarrhythmias: assessment of results of ventricular pacing.白喉性心肌炎合并缓慢性心律失常患者的预后:心室起搏结果评估
Br Heart J. 1994 Aug;72(2):190-1. doi: 10.1136/hrt.72.2.190.
2
Resurgence of diphtheria.白喉的再度流行。
Eur J Epidemiol. 1995 Feb;11(1):95-105. doi: 10.1007/BF01719954.
3
Diphtheria: changing patterns in the developing world and the industrialized world.白喉:发展中世界和工业化世界的变化模式
Eur J Epidemiol. 1995 Feb;11(1):107-17. doi: 10.1007/BF01719955.