Kríz B
Center of Epidemiology and Microbiology, National Institute of Public Health, Prague, Czech Republic.
Cent Eur J Public Health. 2003 Dec;11 Suppl:S7-12.
Diphtheria morbidity in the Czech part of former Czechoslovakia showed a continuous downward trend between 1946 and 1974. Afterwards, sporadic cases of diphtheria were reported in some years. Compulsory vaccination against diphtheria was started in 1946 with a monovaccine, later replaced by bivaccine DiTe. Since 1958, newborns have been vaccinated with DiTePe vaccine. As many as 98% to 100% of the population of age groups under 50 years likely to have been vaccinated have antibody levels > 0.01 lU/ml. About 83% to 88% of the older age groups who represent a naturally immunized population have antibodies as well. This immune status excludes the possibility that diphtheria could spread massively if accidentally imported into the Czech Republic.
在前捷克斯洛伐克的捷克部分，1946年至1974年间白喉发病率呈持续下降趋势。此后，在一些年份报告了散发性白喉病例。1946年开始使用单价疫苗对白喉进行强制接种，后来被二联疫苗DiTe取代。自1958年以来，新生儿一直接种DiTePe疫苗。年龄在50岁以下可能接种过疫苗的人群中，多达98%至100%的人抗体水平>0.01 lU/ml。约83%至88%的老年人群体（即自然免疫人群）也有抗体。这种免疫状况排除了白喉如果意外传入捷克共和国可能大规模传播的可能性。
