Danish R K, Lee P A, Mazur T, Amrhein J A, Migeon C J
Johns Hopkins Med J. 1980 May;146(5):177-84.
This paper documents the case histories of 14 patients with hypogonadotropic hypogonadism and micropenis (penile length below 2.5 SD from the mean for the patient's chronlogical age, or for age corresponding to stage of sexual development). Nine of the patients were raised as males. Five of them received androgen for the purpose of stimulating penile growth: two realized normal adult penile length (-0.2 and -2.1 SD from normal mean length) whereas the other three had penile lengths significantly below the mean (-3.6, -4.6 and -5.2 SD from normal mean length). These data suggest that among hypogonadotropic patients with micropenis, those with prepubertal penile lengths between 2.5 and 3 SD below the mean may develop an adult penis of a length within the normal range. However, for those presenting with a shorter phallus, the expectation is that penile length will remain greater than 2 SD below the mean.
本文记录了14例低促性腺激素性性腺功能减退伴小阴茎患者（阴茎长度低于其实际年龄或性发育阶段相应年龄平均值2.5个标准差以下）的病史。其中9例患者自幼被当作男性抚养。5例患者接受雄激素治疗以刺激阴茎生长：2例成年后阴茎长度达到正常水平（比正常平均长度低0.2和2.1个标准差），而另外3例阴茎长度明显低于平均水平（比正常平均长度低3.6、4.6和5.2个标准差）。这些数据表明，在低促性腺激素性小阴茎患者中，青春期前阴茎长度低于平均水平2.5至3个标准差的患者，成年后阴茎长度可能在正常范围内。然而，对于阴茎更短小的患者，预期其阴茎长度仍会比平均水平低2个标准差以上。
