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EMIC:化学诱变信息的集中来源。

EMIC: a centralized source of chemical mutagenesis information.

作者信息

Shelby M D

出版信息

Environ Health Perspect. 1978 Dec;27:21-5. doi: 10.1289/ehp.782721.

DOI:10.1289/ehp.782721
PMID:738236
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1637307/
Abstract

In 1969, a group of scientists concerned with the health hazards posed by environmental mutagens formed the Environmental Mutagen Society to encourage interest in and the study of mutagens in the human environment. In order to deal effectively with this potential health problem, these scientists saw the need for a centralized source of published information on chemicals tested for mutagenicity and, therefore, set down as one of the immediate functions of the Society, the formation of a registry of chemicals tested for mutagenicity. The Environmental Mutagen Information Center (EMIC) was established at Oak Ridge National Laboratory to fill this information need by collecting, organizing, and making available the international literature on chemical mutagenesis. EMIC is now sponsored by the National Institute of Environmental Health Sciences and the National Cancer Institute. From a simple registry of chemicals tested for mutagenicity, the scope and activities of EMIC have increased greatly. EMIC now processes all publications from the open literature dealing with the genetic effects of any environmental agent except those publications dealing exclusively with ultraviolet light or ionizing radiation.Growing concern for the long-term effects of chemical exposure on human health and interest in the relation between mutagenicity and carcinogenicity are placing ever-increasing demands on this Center. As a result of the early realization of the need for literature control, a modern, specialized information center now serves the information needs of mutagenesis workers and other interested persons around the world.

摘要

1969年,一群关注环境诱变剂对健康危害的科学家成立了环境诱变剂协会,以鼓励人们关注并研究人类环境中的诱变剂。为了有效应对这一潜在的健康问题,这些科学家认为需要有一个集中的已发表信息来源,涵盖经诱变力测试的化学物质,因此将建立一个经诱变力测试的化学物质登记处列为协会的一项近期职能。环境诱变剂信息中心(EMIC)在橡树岭国家实验室成立,通过收集、整理并提供有关化学诱变作用的国际文献来满足这一信息需求。EMIC现在由国家环境健康科学研究所和国家癌症研究所赞助。从一个简单的经诱变力测试的化学物质登记处开始,EMIC的范围和活动已大幅增加。EMIC现在处理公开文献中所有涉及任何环境因子遗传效应的出版物,但专门涉及紫外线或电离辐射的出版物除外。人们日益关注化学物质暴露对人类健康的长期影响,以及对诱变力与致癌性之间关系的兴趣,这对该中心的要求越来越高。由于早期认识到文献管理的必要性,一个现代化的专业信息中心现在满足了全球诱变作用研究人员和其他相关人员的信息需求。

相似文献

1
EMIC: a centralized source of chemical mutagenesis information.EMIC:化学诱变信息的集中来源。
Environ Health Perspect. 1978 Dec;27:21-5. doi: 10.1289/ehp.782721.
2
Potential of plant genetic systems for monitoring and screening mutagens.植物遗传系统用于监测和筛选诱变剂的潜力。
Environ Health Perspect. 1978 Dec;27:181-96. doi: 10.1289/ehp.7827181.
3
Higher plant systems as monitors of environmental mutagens. Proceedings of the NIEHS-sponsored workshop, Marineland, Florida, January 15-19, 1978.高等植物系统作为环境诱变剂的监测器。美国国家环境卫生科学研究所主办的研讨会会议记录,佛罗里达州马林eland,1978年1月15日至19日。
Environ Health Perspect. 1978 Dec;27:1-206. doi: 10.1289/ehp.27-1637304.
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Introduction: utilization of higher plant systems as monitors of environmental mutagens.引言:利用高等植物系统作为环境诱变剂的监测手段。
Environ Health Perspect. 1978 Dec;27:3-6. doi: 10.1289/ehp.78273.
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Environ Mol Mutagen. 2020 Jan;61(1):8-24. doi: 10.1002/em.22313. Epub 2019 Aug 6.
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Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations.用于评估基因组损伤的下一代检测策略:一个概念框架及考量因素
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Mutat Res. 1982 Sep;99(2):243-55.
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A survey of EPA/OPP and open literature data on selected pesticide chemicals tested for mutagenicity. I. Introduction and first ten chemicals.对美国环境保护局/预防、杀虫剂和有毒物质办公室(EPA/OPP)及公开文献中有关经测试具有致突变性的特定农药化学品数据的调查。一、引言及前十种化学品。
Mutat Res. 1993 Oct;297(3):197-233. doi: 10.1016/0165-1110(93)90018-i.
10
Evolution of social concerns and environmental policies for chemical mutagens.
Environ Mol Mutagen. 1989;14 Suppl 16:46-50. doi: 10.1002/em.2850140611.

引用本文的文献

1
Journal notes.期刊笔记。
Bull Med Libr Assoc. 1980 Apr;68(2):259-62.

本文引用的文献

1
A computer-based chemical information system.一个基于计算机的化学信息系统。
Science. 1977 Jan 21;195(4275):253-9. doi: 10.1126/science.831275.