Dearfield K L, Stack H F, Quest J A, Whiting R J, Waters M D
U.S. Environmental Protection Agency, Office of Pesticide Programs, Washington, DC 20460.
Mutat Res. 1993 Oct;297(3):197-233. doi: 10.1016/0165-1110(93)90018-i.
Parties interested in registering a pesticide chemical with the U.S. Environmental Protection Agency's (USEPA's) Office of Pesticide Programs (OPP) must submit toxicity information to support the registration. Mutagenicity data are a part of the required information that must be submitted. This information is available to the public via Freedom of Information requests to the OPP. However, it is felt that this information would be more effectively and widely disseminated if presented in a published medium. Beginning with this publication, sets of mutagenicity data on pesticide chemicals will be periodically published in the Genetic Activity Profile (GAP) format. In addition, mutagenicity data extracted from the currently available open literature is also presented to provide a more complete database and to allow comparisons between the OPP-submitted data and other publicly available information.
有意向美国环境保护局（USEPA）农药项目办公室（OPP）注册农药化学品的各方必须提交毒性信息以支持注册。致突变性数据是必须提交的所需信息的一部分。该信息可通过向OPP提交信息公开申请供公众获取。然而，人们认为，如果以出版媒介呈现此信息，将能更有效且广泛地传播。从本出版物开始，农药化学品的致突变性数据集将定期以遗传活性概况（GAP）格式发布。此外，还呈现了从当前可用的公开文献中提取的致突变性数据，以提供更完整的数据库，并允许对OPP提交的数据与其他公开可用信息进行比较。
