Hain J, Doshi N, Harger J H
Obstet Gynecol. 1980 Jul;56(1):106-9.
A case of herpes simplex infection in the placenta and in an immature infant delivered to a mother with proved genital herpes infection is discussed. Infection occurred without premature rupture of membranes. Viral transmission could be attributed to ascending transcervical infection based on evidence of necrotizing chorioamnionitis in absence of villitis plus extensive and severe involvement of the skin and lungs. Such distinct documentation of transcervical infection in the presence of intact fetal membranes makes it obvious that delivery by cesarean section cannot prevent all cases of neonatal herpes infection.
本文讨论了一例胎盘及未成熟婴儿发生单纯疱疹感染的病例，该婴儿的母亲被证实患有生殖器疱疹感染。感染发生时胎膜未早破。基于在无绒毛炎的情况下存在坏死性绒毛膜羊膜炎以及皮肤和肺部广泛且严重受累的证据，病毒传播可归因于经宫颈上行感染。在胎膜完整的情况下，这种经宫颈感染的明确记录表明，剖宫产并不能预防所有新生儿疱疹感染病例。
