血管活性肠肽（VIP）可抑制前列腺素F2α诱导的兔子宫肌层活性。

Vasoactive intestinal polypeptide (VIP) inhibits prostaglandin-F2 alpha-induced activity of the rabbit myometrium.

作者信息

Ottesen B, Wagner G, Fahrenkrug J

出版信息

Prostaglandins. 1980 Mar;19(3):427-35. doi: 10.1016/0090-6980(80)90076-3.

Abstract

Seven female rabbits ahd myometrial autografts transplanted into ear-chambers. The electrical activity of the graft was recorded and mechanical activity observed. Vasoactive intestinal polypeptide (VIP) dose-dependently inhibited myometrial activity induced by prostaglandin-F2 alpha. This evidence and the occurrence of "VIPergic" nerve fibres, which seem to innervate the myometrial cells, suggest that VIP may play a physiological role in the local control of the myometrial activity.

摘要

七只雌性兔子的子宫肌层自体移植到耳腔中。记录移植物的电活动并观察其机械活动。血管活性肠肽（VIP）剂量依赖性地抑制前列腺素-F2α诱导的子宫肌层活动。这一证据以及似乎支配子宫肌层细胞的“VIP能”神经纤维的存在表明，VIP可能在子宫肌层活动的局部控制中发挥生理作用。