[Incorporation of [1-14C] acetate and [1-14C] glycine into hydrophilic and hydrophobic components of rat brain phospholipids].

The [1-14C]acetate and [1-14C]glycine incorporation into hydrophilic and hydrophobic components of total phospholipids molecules was investigated in the rat brain. The intensity of phospholipid metabolism was identified as a relative specific activity of phospholipids carbon skeleton. The rate of labelling fatty acids and hydrophilic fractions of total phospholipids was different with these precursors. The incorporation of [1-14C]acetate into the carbonic part of fatty acid components was more rapid than into the water soluble fraction. The labelling of the hydrophilic phospholipid fraction was more rapid with [1-14C]glycine than with [1-14C]acetate. There were practically no labelling of fatty acids with the former precursor. These differences between both labelled precursors indicate that the rate of their conversion in the brain tissue is relatively low.