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一氧化二氮和压缩空气对记忆及听觉感知的麻醉作用。

Narcotic effects of nitrous oxide and compressed air on memory and auditory perception.

作者信息

Fowler B, White P L, Wright G R, Ackles K N

出版信息

Undersea Biomed Res. 1980 Mar;7(1):35-46.

PMID:7385446
Abstract

Three experiments were conducted to examine the effects of 35% N2 O (nitrous oxide) on human memory and auditory perception. In Experiment I, dichotic listening performance was found to be impaired. Experiment II used the same technique but was controlled for attenuation of sound transmission in the middle ear. No impairment was found. The perceptual effect found in Experiment I was peripheral, not central, and N2O did not impair short-term memory (STM). Experiment III used one-trial free recall of a word list. The shapes of the serial position curves were interpreted as indicating that N2O impairs long-term memory (LTM) but not STM. Experiment III provided no evidence, using cued recall, that the LTM deficit was due to impaired retrieval. Comparing these results with those for compressed air led to the conclusion that both N2O and hyperbaric nitrogen display an identical pattern of effects. A reason for the decrement found in some N2O STM studies may have been confounding the measurement of STM with that of LTM.

摘要

进行了三项实验,以研究35%的一氧化二氮(N2O)对人类记忆和听觉感知的影响。在实验一中,发现双耳分听表现受损。实验二使用了相同的技术,但对中耳声音传输的衰减进行了控制。未发现受损情况。实验一中发现的感知效应是外周性的,而非中枢性的,并且一氧化二氮不会损害短期记忆(STM)。实验三使用了对单词列表的一次性自由回忆。系列位置曲线的形状被解释为表明一氧化二氮损害长期记忆(LTM)但不损害短期记忆。实验三没有使用线索回忆提供证据表明长期记忆缺陷是由于检索受损所致。将这些结果与压缩空气的结果进行比较得出结论,一氧化二氮和高压氮气都显示出相同的效应模式。在一些一氧化二氮短期记忆研究中发现的下降的一个原因可能是将短期记忆的测量与长期记忆的测量混淆了。

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Narcotic effects of nitrous oxide and compressed air on memory and auditory perception.一氧化二氮和压缩空气对记忆及听觉感知的麻醉作用。
Undersea Biomed Res. 1980 Mar;7(1):35-46.
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