Baisheva S A, Zhalgasbaeva G T, Kaliev Iu Sh, Mezinova N N
Vopr Onkol. 1980;26(5):15-9.
Patients with breast cancer, localized fibroadenomatosis and healthy females were examined for the initial state of cell immunity: the reaction of delayed hypersensitivity to DNCB, the absolute and relative amount of rosette forming cells (T-lymphocytes) and the stimulation of lymphocytes under exposure to PHA. A considerable suppression of cell immunity was shown both in breast cancer patients and in patients with benign tumors. The indices of skin allergic test and reaction of spontaneous rosette formation were nearly identical in both groups of the patients under examination. In case of the reaction of lymphocytes blasttransformation in breast cancer patients the stimulation was found to be much lower than in patients with local fibroadenomatosis.
对乳腺癌患者、局限性纤维瘤病患者和健康女性进行了细胞免疫初始状态的检查:对二硝基氯苯的迟发型超敏反应、玫瑰花结形成细胞(T淋巴细胞)的绝对数量和相对数量以及在暴露于植物血凝素时淋巴细胞的刺激情况。结果显示,乳腺癌患者和良性肿瘤患者的细胞免疫均受到显著抑制。在接受检查的两组患者中,皮肤过敏试验指标和自发玫瑰花结形成反应几乎相同。在乳腺癌患者淋巴细胞转化反应中,发现其刺激程度远低于局限性纤维瘤病患者。