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一氧化碳暴露对兔肺及肺动脉形态的影响。光镜和电镜研究。

The effect of carbon monoxide exposure on morphology of lungs and pulmonary arteries in rabbits. A light- and electron-microscopic study.

作者信息

Hugod C

出版信息

Arch Toxicol. 1980 Feb;43(4):273-81. doi: 10.1007/BF00366183.

DOI:10.1007/BF00366183
PMID:7387387
Abstract

Rabbits were continuously exposed either to 200 parts per million carbon monoxide for 3, 4, and 6 weeks or to 1,900 parts per million carbon monoxide for 5 h. Blind light and transmission electron microscopic investigations showed no morphological changes in the lung parenchyma, lung vasculature or in pulmonary arteries of the exposed animals when compared with controls. The discrepancies with findings previously reported by other authors are discussed.

摘要

将兔子持续暴露于百万分之200的一氧化碳环境中3周、4周和6周，或暴露于百万分之1900的一氧化碳环境中5小时。与对照组相比，盲法光镜和透射电镜检查显示，暴露动物的肺实质、肺血管或肺动脉没有形态学变化。文中讨论了与其他作者先前报道结果的差异。

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A SENSITIVE METHOD FOR THE DETERMINATION OF CARBOXYHAEMOGLOBIN IN A FINGER PRICK SAMPLE OF BLOOD.一种测定手指采血样本中碳氧血红蛋白的灵敏方法。
Br J Ind Med. 1965 Apr;22(2):139-43. doi: 10.1136/oem.22.2.139.
2
Acceleration of spontaneous intimal--subintimal changes in rabbit aorta by a prolonged moderate carbon monoxide exposure.长期适度暴露于一氧化碳加速兔主动脉自发性内膜-中膜下改变。
Acta Pathol Microbiol Scand. 1969;75(3):353-62.
3
Effect of carbon monoxide on function and structure of the lung.
J Appl Physiol. 1969 Jan;26(1):4-12. doi: 10.1152/jappl.1969.26.1.4.
4
Hyperplasia of type 2 pneumocytes and nitrogen dioxide (10 ppm) exposure. A quantitation based on electron photomicrographs.2型肺细胞增生与二氧化氮（10 ppm）暴露。基于电子显微照片的定量分析。
Arch Environ Health. 1971 Jan;22(1):178-88. doi: 10.1080/00039896.1971.10665830.
5
The ultrastructural effects of carbon monoxide inhalation on the rat lung.一氧化碳吸入对大鼠肺脏的超微结构影响
Virchows Arch Pathol Anat Physiol Klin Med. 1965 Aug 13;339(4):283-92. doi: 10.1007/BF00959687.
6
Ultrastructural intimal changes in the rabbit aorta after a moderate carbon monoxide exposure.家兔主动脉在适度一氧化碳暴露后的超微结构内膜变化。
Atherosclerosis. 1972 Jul-Aug;16(1):67-82. doi: 10.1016/0021-9150(72)90009-3.
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Toxicological evaluation of carbon monoxide in humans and other mammalian species.
J Occup Med. 1971 May;13(5):242-55.
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Experientia. 1972 Jul 15;28(7):828-31. doi: 10.1007/BF01923157.
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