在连续传代移植过程中伴刀豆球蛋白A介导的激素依赖性小鼠乳腺肿瘤细胞凝集作用的变化
Changes in concanavalin A-mediated agglutination of hormone-dependent mouse mammary tumour cells during serial transplantation.
作者信息
Sluyser M, van der Valk M, van Blitterswijk W J
出版信息
Br J Cancer. 1980 Mar;41(3):348-55. doi: 10.1038/bjc.1980.57.
Abstract
The concanavalin A-mediated agglutinability of GR mouse mammary tumour cells changes during serial transplantation of the tumours. Hormone-dependent cells in general have a lower agglutinability than hormone-independent cells. However, changes have also been observed in the histology of the tumours during serial transplantation, which as such may also alter the Con A-mediated agglutinability of the tumour cells.
摘要
刀豆球蛋白A介导的GR小鼠乳腺肿瘤细胞的凝集性在肿瘤的连续移植过程中会发生变化。一般来说，激素依赖性细胞的凝集性低于激素非依赖性细胞。然而，在连续移植过程中肿瘤的组织学也观察到了变化，这本身也可能改变肿瘤细胞的刀豆球蛋白A介导的凝集性。
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