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The antiandrogenic effect of progesterone on the hamster flank organ.

作者信息

Vermorken A J, Goos C M, Roelofs H M

出版信息

Br J Dermatol. 1980 Apr;102(4):455-60. doi: 10.1111/j.1365-2133.1980.tb06560.x.

DOI:10.1111/j.1365-2133.1980.tb06560.x
PMID:7387888
Abstract

Progesterone, topically applied, prevents the stimulation of the hamster flank organ by testosterone, but not by dihydrotestosterone. 5 alpha-Dihydroprogesterone does not prevent stimulation by either of the two androgenic hormones. Neither progesterone nor 5 alpha-dihydroprogesterone stimulate the flank organ to any extent. Implications on the use of progesterone in acne therapy are discussed.

摘要

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