Suppr超能文献

卡介苗诱导的小鼠胸腺皮质以及脾脏和淋巴结中胸腺依赖区大小的变化。

BCG-induced changes in size of thymic cortex and thymus-dependent areas in spleen and lymph nodes of mice.

作者信息

Meyer E M, Grundmann E

出版信息

Clin Exp Immunol. 1980 Jan;39(1):60-5.

PMID:7389199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1537931/
Abstract

Significant changes in the size of thymic cortex and of thymus-dependent areas (TDA) in spleen and lymph nodes, were revealed by histomorphometry after intraperitoneal injection of BCG into young-adult BALB/c mice. Reactions of the thymic cortex were found to be biphasic with initial involution and subsequent hyperplasia. TDA in the spleen showed a transient involution with almost complete regeneration at the end of the experiment. The response of TDA in lymph nodes was characterized by pronounced and persistent hyperplasia. The functional significance of these BCG-induced changes of lymphoid tissue compartments is discussed.

摘要

对年轻成年BALB/c小鼠腹腔注射卡介苗后，通过组织形态计量学发现，胸腺皮质以及脾脏和淋巴结中胸腺依赖区（TDA）的大小发生了显著变化。胸腺皮质的反应呈双相性，最初是退化，随后是增生。脾脏中的TDA出现短暂退化，在实验结束时几乎完全再生。淋巴结中TDA的反应特征是明显且持续的增生。本文讨论了这些卡介苗诱导的淋巴组织区室变化的功能意义。

相似文献

1
BCG-induced changes in size of thymic cortex and thymus-dependent areas in spleen and lymph nodes of mice.卡介苗诱导的小鼠胸腺皮质以及脾脏和淋巴结中胸腺依赖区大小的变化。
Clin Exp Immunol. 1980 Jan;39(1):60-5.
2
[Studies of the effects of BCG and Corynebacterium parvum vaccines in experimental infection of mice with influenza virus. Foot pad test, splenic indicator and histologic changes in the thymus gland, spleen and lymph nodes].
Med Dosw Mikrobiol. 1989;41(2):92-9.
3
Histologic reactions of the thymus, spleen, liver and lymph nodes to intravenous and subcutaneous BCG injections.胸腺、脾脏、肝脏及淋巴结对静脉注射和皮下注射卡介苗的组织学反应。
Biomedicine. 1975 Mar;22(2):112-21.
4
Comparative study of the histologic reactions to intravenous injections of heat-killed Pseudomonas aeruginosa and of BCG.
Biomedicine. 1979 Oct;30(4):200-5.
5
Cellular changes in the lymphoreticular tissues of C57L/J mice infected with Echinococcus multilocularis cysts.感染多房棘球绦虫囊肿的C57L/J小鼠淋巴网状组织中的细胞变化
Immunology. 1978 May;34(5):831-9.
6
[Morphometric analysis of lymphoid organs in the hypophysectomized rat].[垂体切除大鼠淋巴器官的形态计量分析]
Boll Soc Ital Biol Sper. 1978 Oct 15;54(19):1893-9.
7
Pregnancy-induced involution of the thymus can be prevented by immunizing with paternal skin grafts: a strain-dependent effect.通过用父系皮肤移植进行免疫可预防妊娠诱导的胸腺退化：一种品系依赖性效应。
Clin Exp Immunol. 1979 Mar;35(3):421-4.
8
Lymphoid response to pregnancy and pseudopregnancy in the rat.大鼠对妊娠和假孕的淋巴反应。
J Anat. 1979 Jun;128(Pt 4):837-45.
9
Modulation of the effects of cyclophosphamide on the lymphoid system of mice by double-stranded RNA.双链RNA对环磷酰胺作用于小鼠淋巴系统效果的调节
Folia Biol (Praha). 1985;31(1):59-62.
10
Effect of 2-fluorohistidine upon leukocytopoiesis in mice.2-氟组氨酸对小鼠白细胞生成的影响。
Res Commun Chem Pathol Pharmacol. 1977 Mar;16(3):507-22.

引用本文的文献

1
Resistance and susceptibility of mice to bacterial infection: histopathology of listeriosis in resistant and susceptible strains.小鼠对细菌感染的抵抗力和易感性：抗性和易感品系中李斯特菌病的组织病理学
Infect Immun. 1980 Dec;30(3):851-61. doi: 10.1128/iai.30.3.851-861.1980.
2
The immunologic and immunotherapeutic sequelae of intraperitoneal BCG. II: Serial changes in spleen weight, morphology, cell populations and in vitro mitogen responses.腹腔内注射卡介苗的免疫及免疫治疗后遗症。II：脾脏重量、形态、细胞群体及体外有丝分裂原反应的系列变化。
Ir J Med Sci. 1983 Aug;152(8):307-10. doi: 10.1007/BF02945303.
3
Flow microfluorometry analysis of alterations in T-lymphocyte subsets during murine listeriosis.小鼠李斯特菌病期间T淋巴细胞亚群变化的流式微量荧光分析
Infect Immun. 1984 Aug;45(2):372-7. doi: 10.1128/iai.45.2.372-377.1984.

本文引用的文献

1
A HISTOLOGICAL STUDY OF LYMPH NODES DURING THE DEVELOPMENT OF DELAYED HYPERSENSITIVITY TO SOLUBLE ANTIGENS.可溶性抗原迟发型超敏反应发生过程中淋巴结的组织学研究
Int Arch Allergy Appl Immunol. 1965;27:199-212. doi: 10.1159/000229612.
2
The effect of localized injection of adjuvant material on the draining lymph node. II. Circulating lymphocytes.佐剂材料局部注射对引流淋巴结的影响。II. 循环淋巴细胞
Immunology. 1970 May;18(5):663-70.
3
Distinctive medullary and germinal center proliferative patterns in mouse lymph nodes after regional primary and secondary stimulation with tetanus toxoid.破伤风类毒素局部初次和二次刺激后小鼠淋巴结中独特的髓质和生发中心增殖模式。
J Immunol. 1974 Jun;112(6):1961-70.
4
Splenic regulation of lymphocyte trapping in lymph nodes draining tumor grafts.脾脏对肿瘤移植引流淋巴结中淋巴细胞捕获的调节作用。
J Immunol. 1975 Aug;115(2):345-50.
5
A mathematical model in immunoregulation where the spleen has a pivotal role.一种脾脏起关键作用的免疫调节数学模型。
J Theor Biol. 1976 Sep 21;61(2):363-76. doi: 10.1016/0022-5193(76)90024-2.
6
Network of immune-neuroendocrine interactions.免疫-神经内分泌相互作用网络
Clin Exp Immunol. 1977 Jan;27(1):1-12.
7
Present knowledge of immunization against tuberculosis.当前关于结核病免疫接种的知识。
Bull World Health Organ. 1976;54(3):255-69.
8
Studies on the immunogical effects of BCG and its components: theoritical and therapeutic implications.卡介苗及其成分的免疫效应研究：理论与治疗意义
Biomedicine. 1976;24(4):209-13.
9
Effects of BCG on lymphocyte trapping.卡介苗对淋巴细胞捕获的影响。
J Immunol. 1976 Jun;116(6):1587-91.
10
Antigen specific lymphocyte transformation, delayed hypersensitivity and protective immunity. I. Kinetics of the response.抗原特异性淋巴细胞转化、迟发型超敏反应与保护性免疫。I. 反应动力学。
Cell Immunol. 1978 May;37(2):315-26. doi: 10.1016/0008-8749(78)90200-9.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验