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新生儿对应激情况的心血管适应:缺氧对新生仔猪和14日龄仔猪的影响(作者译)

[Cardiovascular adaptation of the newborn to stress situations: effects of hypoxia on newborn and 14-day-old piglets (author's transl)].

作者信息

Angerpointner T, Linderkamp O, Stallinger H, Riegel K

出版信息

Chir Forum Exp Klin Forsch. 1980:53-6.

PMID:7389481
Abstract

-Newborn and 14-day-old piglets (in a developmental stage equivalent to that of a 3-month-old infant) compensate sustained hypoxemia by increasing cardiac performance. -This compensation can be maintained for only roughly 30 min. -Newborn piglets free from hypoxemia are able to tolerate the stress of anesthesia, artificial respiration, and operation significantly longer than those with additional hypoxemia. -14 day-old piglets without hypoxemia are not able to tolerate the stress of anesthesia, artificial respiration, and operation longer than those with additional hypoxemia. -The reactions of the cardiovascular system to anesthesia, artificial respiration, and operation in present or absent additional hypoxemia are qualitatively identical and are also identical in time in the newborn hypoxic, the 14-day-old hypoxic, and normoxic animals, whereas they appear significantly later in newborn control piglets.

摘要

-新生仔猪和14日龄仔猪(发育阶段相当于3个月大的婴儿)通过提高心脏功能来代偿持续性低氧血症。-这种代偿只能维持大约30分钟。-未患低氧血症的新生仔猪比患有低氧血症的仔猪能够显著更长时间地耐受麻醉、人工呼吸和手术应激。-未患低氧血症的14日龄仔猪比患有低氧血症的仔猪耐受麻醉、人工呼吸和手术应激的时间短。-在有或无额外低氧血症的情况下,心血管系统对麻醉、人工呼吸和手术的反应在性质上是相同的,在新生低氧、14日龄低氧和正常动物中反应时间也相同,而在新生对照仔猪中反应明显延迟。

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