Shearer T R, Britton J L, DeSart D J
Environ Health Perspect. 1980 Feb;34:219-21. doi: 10.1289/ehp.8034219.
Uptake of cadmium into molar enamel and dentin from rats receiving cadmium in their drinking water was markedly elevated and proportional to the amount of cadmium in the drinking water. Post-developmental cadmium did not influence caries development or alter the cariostatic effectiveness of fluoridated drinking water. The data indicate that the absolute concentration of cadmium in teeth is not predictive or cadmium-induced caries and that the critical period for caries promotion by cadmium may be during the developmental rather than the post-developmental period of tooth formation.
从饮用水中摄取镉的大鼠，其臼齿釉质和牙本质中的镉摄取量显著升高，且与饮用水中的镉含量成正比。发育后摄入的镉不会影响龋齿的发展，也不会改变含氟饮用水的防龋效果。数据表明，牙齿中镉的绝对浓度并不能预测镉诱发的龋齿，镉促进龋齿发生的关键时期可能是在牙齿形成的发育阶段而非发育后阶段。
