Shearer T R, Britton J L, DeSart D J, Johnson J R
Arch Environ Health. 1980 May-Jun;35(3):176-80. doi: 10.1080/00039896.1980.10667488.
Cadmium injections during molar tooth development in the rat were strongly caries-promoting in female rats. Cadmium also partially negated the cariostatic effect of fluoridated drinking water in both male and female rats. The mechanism for the caries-promoting properties of cadmium is unknown, but may be related to cadmium uptake into enamel and dentin. Cadmium was taken up into molar enamel and dentin in proportion to the amount of cadmium administered, but cadmium did not influence uptake of fluoride onto eruted enamel. Calcium and ash concentrations in molar enamel were not altered by cadmium administration.
在大鼠磨牙发育期间注射镉，对雌性大鼠具有很强的致龋作用。镉还部分抵消了氟化饮水对雄性和雌性大鼠的防龋效果。镉的促龋特性机制尚不清楚，但可能与镉进入牙釉质和牙本质有关。镉按给药量的比例被吸收到磨牙的牙釉质和牙本质中，但镉并不影响氟在酸蚀牙釉质上的吸收。给予镉不会改变磨牙牙釉质中的钙和灰分浓度。
