Rostoker W, Galante J O, Lereim P
J Biomed Mater Res. 1978 Nov;12(6):823-9. doi: 10.1002/jbm.820120605.
Alloys of cast Co-Cr-Mo, wrought Co-Cr-W, wrought, Co-Ni-Cr-Mo(MP35N), Ti-60% Al-4% V, and graphite were incorporated in specimens which simulated both a couple and a crevice corrosion condition. These specimens were implanted in a dog for 30 months. Post-sacrifice examination showed no substantial evidence of corrosion activity on the surfaces of the metals except for a tarnish film on the titanium alloy specimens. The presence of the tarnish film is taken as more evidence of corrosion activity and this correlated with a thicker average fibrous membrane, cellular activity in and near the fibrous membrane, and some increased vascularity. These must be regarded as preliminary observations.
铸造钴铬钼合金、锻造钴铬钨合金、锻造钴镍铬钼合金(MP35N)、钛-60%铝-4%钒合金以及石墨被制成模拟偶合和缝隙腐蚀条件的试样。这些试样被植入一只狗体内30个月。处死动物后的检查表明,除了钛合金试样表面有一层锈蚀膜外,没有实质性证据表明金属表面存在腐蚀活性。锈蚀膜的存在被视为腐蚀活性的更多证据,这与较厚的平均纤维膜、纤维膜内及附近的细胞活性以及一些血管增多有关。这些都必须被视为初步观察结果。