Contaldo F, Rocco P, Mancini M
Int J Obes. 1980;4(1):43-8.
Left-arm thermography and adipose-tissue biopsy of triceps skinfold have been performed in seven patients with obesity of early onset (EO), seven with maturity-onset obesity (MO) and seven non-obese control subjects (C). Obese patients were within the same range for age, physical activity, excess body-fat content and skinfold thickness; mean fat-cell diameter was found to be significantly higher in the group MO than either EO (P less than 0.05) or C subjects (P less than 0.01). Colour thermograms, as evaluated by a well-standardized score system, showed that skin temperature was higher in MO than in EO or C cases (P less than 0.05). The combination of fat-cell hyperplasia and lower thermal losses from the skin, indicative of a lower rate of energy expenditure, may explain the higher frequency of therapeutically refractory cases in EO than MO patients.
对7例早发性肥胖(EO)患者、7例成年起病型肥胖(MO)患者和7例非肥胖对照者(C)进行了左臂热成像检查和肱三头肌皮褶脂肪组织活检。肥胖患者在年龄、身体活动、体脂过量含量和皮褶厚度方面处于相同范围;发现MO组的平均脂肪细胞直径显著高于EO组(P<0.05)或C组(P<0.01)。通过标准化评分系统评估的彩色热成像图显示,MO组的皮肤温度高于EO组或C组(P<0.05)。脂肪细胞增生与皮肤较低的热损失相结合,表明能量消耗率较低,这可能解释了EO患者比MO患者治疗难治性病例的发生率更高的原因。