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枸橼酸氯米芬与绒毛膜促性腺激素治疗后妊娠的前景及质量。53例连续病例(作者译)

[The outlook and the quality of pregnancies resulting from treatment with clomiphene citrate and chorionic gonadotrophin. 53 consecutive cases (author's transl)].

作者信息

Senez P, Gillet J Y

出版信息

J Gynecol Obstet Biol Reprod (Paris). 1978 May-Jun;7(5):987-90.

PMID:739128
Abstract

The study of 53 pregnancies which were the result of induction of ovulation using a standard treatment with 100 mg of clomiphene citrate and 3 injections of 1,500 I.U. of H.C.G. showed no increase in the risk of fetal malformation. Before treatment this same group of women has a high risk of spontaneous abortion (43p. 100). After treatment in 53 conceptions 7 ended with an abortion which, is 13p. 100. The risks which follow this treatment are above all dominated by the definite increase in twin pregnancies and in prematurity which follows from this factor.

摘要

对53例采用100毫克枸橼酸氯米芬标准治疗并注射3次1500国际单位人绒毛膜促性腺激素诱导排卵而怀孕的研究表明,胎儿畸形风险并未增加。治疗前,同一组女性自然流产风险较高(每100例中有43例)。治疗后,53次怀孕中有7例以流产告终,即每100例中有13例。这种治疗带来的风险首先是双胎妊娠的明显增加以及由此导致的早产。

相似文献

1
[The outlook and the quality of pregnancies resulting from treatment with clomiphene citrate and chorionic gonadotrophin. 53 consecutive cases (author's transl)].枸橼酸氯米芬与绒毛膜促性腺激素治疗后妊娠的前景及质量。53例连续病例(作者译)
J Gynecol Obstet Biol Reprod (Paris). 1978 May-Jun;7(5):987-90.
2
[The outcome in pregnancies resulting after the induction of ovulation 519 pregnancies (author's transl)].[促排卵后妊娠的结局 519 例妊娠(作者译)]
J Gynecol Obstet Biol Reprod (Paris). 1979 Jun;8(4):333-42.
3
Addition of human chorionic gonadotropin to clomiphene citrate ovulation induction therapy does not improve pregnancy outcomes and luteal function.在枸橼酸氯米芬促排卵治疗中添加人绒毛膜促性腺激素并不能改善妊娠结局和黄体功能。
Fertil Steril. 2006 Mar;85(3):783-6. doi: 10.1016/j.fertnstert.2005.09.018.
4
[Development of pregnancy after use of ovulation inducers].[使用促排卵药物后妊娠的发生情况]
Rev Fr Gynecol Obstet. 1974 Mar;69(3):181-5.
5
[Serial determination of hormones in pregnancies following induction of ovulation with clomiphene and gonadotropins (author's transl)].用克罗米芬和促性腺激素诱导排卵后妊娠期间激素的系列测定(作者译)
Geburtshilfe Frauenheilkd. 1979 Mar;39(3):228-38.
6
[Multiple pregnancies. Apropos of 37 cases].[多胎妊娠。关于37例]
J Gynecol Obstet Biol Reprod (Paris). 1980;9(2):243-8.
7
Women with ovulatory dysfunction undergoing ovarian stimulation with clomiphene citrate for intrauterine insemination may benefit from administration of human chorionic gonadotropin.接受枸橼酸氯米芬卵巢刺激以进行宫内人工授精的排卵功能障碍女性,可能会从注射人绒毛膜促性腺激素中获益。
Fertil Steril. 2005 May;83(5):1510-6. doi: 10.1016/j.fertnstert.2004.11.049.
8
A reduction in multiple pregnancies following the use of a clomiphene citrate: human gonadotrophin sequence.使用枸橼酸氯米芬-人促性腺激素序列后多胎妊娠的减少。
Acta Eur Fertil. 1976 Mar;7(1):83-7.
9
The frequency of ovular resorption during the first trimester of twin pregnancy.双胎妊娠孕早期胚珠吸收的频率。
Acta Genet Med Gemellol (Roma). 1979;28(4):271-2.
10
Ovulation induction with gonadotropins in women with polycystic ovary disease.
J Reprod Med. 1991 Jan;36(1):61-4.

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1
Gonadotrophin and the human secondary sex ratio.促性腺激素与人类出生性别比
Br Med J. 1980 Sep 13;281(6242):711-2. doi: 10.1136/bmj.281.6242.711.