[Serial determination of hormones in pregnancies following induction of ovulation with clomiphene and gonadotropins (author's transl)].

The HCG, HPL, progesterone and oestriol levels in the serum were determined in 33 pregnancies following induction of ovulation with clomiphene and in 7 pregnancies following induction of ovulation with gonadotropins. During these pregnancies bleeding, premature labour and toxaemia occurred more often in women who became pregnant after induction of ovulation with clomiphene. The progesterone and oestriol levels were increased up to the 12th week of gestation, whereas the HCG and HPL levels remained normal. After induction of ovulation with gonadotropins the progesterone levels remained elevated until the 19th week of gestation whereas the levels of HCG and HPL and oestriol remained normal. The course of the pregnancy in a patient who had Meigs-syndrome after treatment with gonadotropins was presented. Our results show that the hormonal evaluation of pregnancies after induction of ovulation is best accomplished during the first three months by HCG and HPL titres and during the second half of the pregnancy according to the same criteria as in other pregnancies.