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[医学、临床化学和临床生物化学中的质谱分析及联合技术。1977年11月14日至15日于图宾根大学医学诊所召开的会议报告(作者译)]

[Mass spectrometry and combined techniques in medicine, clinical chemistry and clinical biochemistry. Report on the conference at the Medizinische Klinik of the University of Tübingen on November 14--15, 1977 (author's transl)].

作者信息

Liebich H M

出版信息

J Clin Chem Clin Biochem. 1978 Dec;16(12):677-86.

PMID:739237
Abstract

Mass spectrometry, especially in combination with gas chromatography, is the most flexible and powerful analytical technique available today for organic substances, with the exception of macromolecules. It is distinguished by vary high sensitivity combined with high specificity, and enables the identification and quantification of substances in biological material even in very low concentration. The conference was divided into five sessions: Main areas of application, Hormones and active substances, Profile analyses, Methodical and theoretical aspects, Pharmacological and toxicological applications. It was the goal of the symposium to gather scientists and clinicians and to define the scope and place of mass spectrometry in clinical chemical and medical research, and in routine analysis, and to identify the kind of problems it can help to solve.

摘要

质谱分析法,尤其是与气相色谱法联用,是当今除大分子物质外可用于分析有机物质的最灵活、最强大的分析技术。它的特点是灵敏度极高且特异性强,即使生物材料中物质的浓度极低,也能对其进行鉴定和定量分析。会议分为五个部分:主要应用领域、激素与活性物质、谱图分析、方法学与理论方面、药理与毒理学应用。本次研讨会的目的是召集科学家和临床医生,明确质谱分析法在临床化学和医学研究以及常规分析中的范围和地位,并确定它能够帮助解决的问题类型。

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