Hammett-Stabler Catherine A, Garg Uttam
Department of Pathology & Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599-7525, USA.
Methods Mol Biol. 2010;603:1-7. doi: 10.1007/978-1-60761-459-3_1.
Clinical laboratories around the world are recognizing the power of mass spectrometry. This technique, especially when coupled to gas chromatography or liquid chromatography, is revolutionizing the analysis of many analytes. Unlike many other techniques which measure one analyte at a time, these techniques can measure multiple analytes (>40) at one time. In recent years the scope of testing using these techniques has expanded from toxicological purposes to newborn screening to hormones, proteins, and enzymes. It is not uncommon any more to see mass spectrometry being used in the routine clinical laboratories.
世界各地的临床实验室都认识到了质谱分析法的强大功能。这项技术，尤其是与气相色谱法或液相色谱法结合使用时，正在彻底改变许多分析物的分析方式。与许多其他一次只能测量一种分析物的技术不同，这些技术可以一次测量多种分析物（>40种）。近年来，使用这些技术进行检测的范围已从毒理学目的扩展到新生儿筛查，再到激素、蛋白质和酶。如今在常规临床实验室中使用质谱分析法已屡见不鲜。
