Tiltman A J
J Pathol. 1978 Oct;126(2):79-83. doi: 10.1002/path.1711260204.
Two hundred and twenty-four biopsies from 151 patients with urinary bladder neoplasms have been studied in order to investigate the incidence of and possible causes for the infiltration of eosinophils. Cases of schistosomiasis were excluded from this study. Of these biopsies, 16 showed a heavy infiltrate 26 a moderate, 61 minimal and 121 no eosinophilic infiltrate. No correlation could be found between the degree of infiltrate and age, sex or tumour type. There was some statistically significant correlation between the eosinophilic infiltrate and stromal invasion and/or tumour necrosis. There was a strong statistical correlation between this infiltrate and previous trauma (biopsy) which was supported by the study of bladder biopsies from patients without neoplasms.
为了研究嗜酸性粒细胞浸润的发生率及可能原因，对151例膀胱肿瘤患者的224份活检样本进行了研究。本研究排除了血吸虫病病例。在这些活检样本中，16份显示重度浸润，26份显示中度浸润，61份显示轻度浸润，121份无嗜酸性粒细胞浸润。浸润程度与年龄、性别或肿瘤类型之间未发现相关性。嗜酸性粒细胞浸润与基质浸润和/或肿瘤坏死之间存在一些统计学上的显著相关性。这种浸润与既往创伤（活检）之间存在很强的统计学相关性，这一点在对无肿瘤患者的膀胱活检研究中得到了支持。
