Lowe D, Fletcher C D, Gower R L
J Clin Pathol. 1984 May;37(5):500-2. doi: 10.1136/jcp.37.5.500.
Tumour eosinophilia is an uncommon but striking phenomenon which has been found in many tumours, mostly of large cell type or squamous differentiation. The incidence, appearance and importance of tumour eosinophilia in the bladder are described. Eosinophilia is commoner in deeply invasive tumours and in tumours showing squamous metaplasia. Transitional cell carcinomas with eosinophilia have a better prognosis than those without, but this improvement is not seen in squamous cell carcinomas of the bladder. When eosinophilia is found on superficial biopsies of a bladder tumour, the possibility of muscle invasion should be considered.
肿瘤嗜酸性粒细胞增多是一种罕见但显著的现象，已在许多肿瘤中发现，大多为大细胞型或鳞状分化型。本文描述了膀胱肿瘤嗜酸性粒细胞增多的发生率、表现及重要性。嗜酸性粒细胞增多在浸润性深的肿瘤和表现为鳞状化生的肿瘤中更为常见。伴有嗜酸性粒细胞增多的移行细胞癌比不伴有者预后更好，但膀胱鳞状细胞癌未见这种改善。当在膀胱肿瘤的浅表活检中发现嗜酸性粒细胞增多时，应考虑肌肉浸润的可能性。
