Benabid A L, Persat J C, de Rougemont J, Chirossel J P, Barge M
J Physiol (Paris). 1978;74(4):369-78.
The authors have demonstrated experimentally in dogs that, in all cases, the cortical venous pressure (Pvco) is higher than the intracranial pressure (PIC), which always remains higher than the sagittal sinus venous pressure (PSLS). The difference between Pvco and PIC remains statistically equal to 8 mm Hg and can be explained by the "Vascular Waterfall" phenomenon; during Queckenstedt's test, the intracranial venous volume does not change, and is not the cause for the increase of PIC; this increase is due to the constancy of the difference between PIC and PSLS, which is induced by the resorption of CSF through the arachnoïd villi. Increases in Pvco and PIC are shown to be equal to 70% and &2% respectively of the change in PSLS. Any other factor that increases PIC (injections in the cisterna magna, pharmacological effects) does not change PSLS, which remains equal to zero. As long as the cerebral blood flow is constant, the increase in cerebro-vascular resistance of the veins at the site of their junction to the sagittal sinus must be compensated upstream by a vasodilatation, which leads to a new distribution of the pressures along the cerebro-vascular bed.
作者们已在狗身上通过实验证明，在所有情况下，皮质静脉压（Pvco）均高于颅内压（PIC），而颅内压始终高于矢状窦静脉压（PSLS）。Pvco与PIC之间的差异在统计学上始终等于8 mmHg，这可以用“血管瀑布”现象来解释；在奎肯施泰特试验期间，颅内静脉容量不变，并非PIC升高的原因；这种升高是由于PIC与PSLS之间差异的恒定，这是由脑脊液通过蛛网膜绒毛的吸收所诱发的。结果表明，Pvco和PIC的升高分别相当于PSLS变化的70%和82%。任何其他增加PIC的因素（如在小脑延髓池注射、药理作用）都不会改变PSLS，PSLS仍等于零。只要脑血流量恒定，静脉在与矢状窦交界处的脑血管阻力增加，就必须在其上游通过血管扩张来补偿，这会导致沿脑血管床的压力重新分布。
