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[粉尘螨蜱蛋白抗原的凝胶过滤分析]

[Gel filtration analysis of the protein antigens of Dermatophagoides pteronyssinus ticks].

作者信息

Ivanov L N, Undritsov M I, Bagrova N V

出版信息

Biull Eksp Biol Med. 1980 Jun;89(6):712-4.

PMID:7397361
Abstract

Gel filtration analysis was used to study the antigenous composition and molecular weight of the culture extract from the ticks D. pteronyssinus. The highest allergenic and immunochemical activity was shown by elution fractions I and II taken together. Their activity exceeded that of the whole extract by 69%. The molecular weight of antigens entering elution fractions I and II is about 49000--28000. Fraction III is immunochemically inert and exhibits little allergenic activity.

摘要

采用凝胶过滤分析法研究了柏氏禽刺螨培养提取物的抗原组成和分子量。洗脱组分I和II合在一起显示出最高的致敏和免疫化学活性。它们的活性比整个提取物高出69%。进入洗脱组分I和II的抗原分子量约为49000 - 28000。组分III在免疫化学上无活性,致敏活性也很低。

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