Ross D W, Bardwell A
Blood Cells. 1980;6(3):455-70.
Automated flow cytochemistry is a new technology which when applied to the problem of the white cell differential in leukemic patients extends the quantitative measure of both leukemic and nonleukemic cells over a greater range of concentrations. The Technicon Instruments Corporation, Hemalog-D automated white cell differential counter was employed in an investigation of leukemic patients with the following results: (a) There is an improvement in the diagnostic accuracy of subclassifying leukemias because of the use of cytochemistry. (b) Automated cytochemistry has increased sensitivity for the detection of both leukemic blasts and mature neutrophils in leukopenic patients, thus aiding in the distinction between early remission and persistent leukemia. (c) The increased precision of the differential demonostrates a linear correlation between the kinetics of different cell types not previously noted.
自动流式细胞化学是一项新技术，应用于白血病患者白细胞分类问题时，能在更大浓度范围内对白血病细胞和非白血病细胞进行定量测量。在一项对白血病患者的研究中使用了Technicon仪器公司的Hemalog - D自动白细胞分类计数器，结果如下：(a) 由于使用了细胞化学方法，白血病亚分类的诊断准确性有所提高。(b) 自动细胞化学提高了对白细胞减少患者中白血病原始细胞和成熟中性粒细胞的检测灵敏度，有助于区分早期缓解和持续性白血病。(c) 分类精度的提高表明不同细胞类型的动力学之间存在以前未被注意到的线性相关性。
