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白细胞分类:化疗患者中细胞类型的耦合

White cell differential: coupling of cell types in patients undergoing chemotherapy.

作者信息

Ross D W, Bardwell A

出版信息

Blood Cells. 1982;8(3):549-52.

PMID:7159764
Abstract

The peripheral white blood cell differential counts in patients undergoing chemotherapy showed an unexpected partial correlation between the various cell classes during wide swings in the absolute cell number. These observations were made using the technique of automated flow cytochemistry on a 10,000 cell count Hemalog-D, which increases the statistical precision and permits differential counts in leukopenic patients. The data demonstrated that the white cell types do not behave as independent variables and suggest that the white blood cell differential count in the peripheral blood during chemotherapy may be in part altered by factors unrelated to cell production or destruction kinetics.

摘要

接受化疗患者的外周血白细胞分类计数显示,在绝对细胞数大幅波动期间,各类细胞之间存在意外的部分相关性。这些观察结果是使用自动流式细胞化学技术在对10000个细胞进行计数的Hemalog-D仪器上得出的,该技术提高了统计精度,并允许对白细胞减少症患者进行分类计数。数据表明,白细胞类型并非独立变量,这表明化疗期间外周血白细胞分类计数可能部分受到与细胞生成或破坏动力学无关因素的影响。

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