Kingsley T C
Blood Cells. 1980;6(3):483-7.
Utilizing normal patient blood samples, two automated differential pattern recognition systems, the ADC-500 and the Hematrak 360, were compared in a duplicate study with the manual eye method, using spun and wedge smear preparations. The study showed a superior precision for the 500-cell differential, but occasional data points with spun smears were unusually drifted from the central cluster for both the manual and instrument methods. Analysis of the data uncovered at least two reasons for these unusual outliers: "star artifacts" and warped glass slides. The importrance of these method-related artifacts are discussed, alo ng with the future of the 500-cell differential with today's automated technology.
利用正常患者血液样本，在一项重复研究中，将两种自动鉴别模式识别系统ADC - 500和血细胞分析仪360与手工目视法进行比较，使用的是推片和楔形涂片制备方法。研究表明，500细胞鉴别具有更高的精度，但对于手工和仪器方法，推片涂片的一些数据点偶尔会异常偏离中心聚类。对数据的分析揭示了这些异常离群值的至少两个原因：“星状伪像”和玻片翘曲。讨论了这些与方法相关的伪像的重要性，以及500细胞鉴别在当今自动化技术下的未来。
