Franke S, Winter G, Klee W E
Leber Magen Darm. 1978 Dec;8(6):361-4.
208 gallstones were collected in sequence and subjected to chemical analysis. Only 10.6% of these stones turned out to be purely composed by cholesterol and only these can be considered to be suited for therapy with chenodesoxycholic acid (CDC). Gallstones composed exclusively by cholesterol cannot be identified in vivo; therapy with CDS has to be followed closely by multiple X-ray and laboratory examinations; in addition there are many relapses after therapy with CDC. For these reasons we still tend to prefer surgery as the therapy of choice in gallstone disease.
依次收集了208颗胆结石并进行化学分析。结果发现,这些结石中只有10.6%是纯胆固醇结石,只有这些结石才被认为适合用鹅去氧胆酸(CDC)治疗。纯胆固醇结石无法在体内识别;使用CDS治疗必须紧接着进行多次X光和实验室检查;此外,使用CDC治疗后有很多复发情况。由于这些原因,我们在胆结石疾病的治疗中仍然倾向于首选手术。