Seifert E
Leber Magen Darm. 1977 Oct;7(5):324-7.
Patients under 50 years without risk factors carrying gallstones should be operated upon for the following reasons: (1) These patients will have complications in up to 40% of cases with increasing age; (2) only 18% of patients are without complaints after a duration of this disease of twenty years; (3) mortality of surgery is 1,06% in patients with no other risk factors. Patients at risk for other reasons, with a functional gallbladder and carrying calcium-free stones should be treated with chenodesoxycholic acid. Patients at risk for other reasons carrying residual stones after cholecystectomy, or suffering from stenosis of the papilla, or harboring stones in the choledochus after choledochoduodenostomy should be subjected to endoscopic papillotomy. Patients at risk for other reasons suffering from cholecystolithiasis or choledocholithiasis should be subjected at first to endoscopic papillotomy, and only thereafter to cholecystectomy. This will decrease the risk of surgery.
50岁以下无危险因素的胆结石患者应接受手术,原因如下:(1)随着年龄增长,这些患者高达40%会出现并发症;(2)病程长达20年后,只有18%的患者无不适症状;(3)无其他危险因素的患者手术死亡率为1.06%。因其他原因有风险、胆囊功能正常且携带无钙结石的患者,应使用鹅去氧胆酸治疗。因其他原因有风险、胆囊切除术后有残余结石、患有乳头狭窄或胆总管十二指肠吻合术后胆总管有结石的患者,应接受内镜乳头切开术。因其他原因有风险、患有胆囊结石或胆总管结石的患者应首先接受内镜乳头切开术,然后再进行胆囊切除术。这将降低手术风险。