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矿物油、植物油和硫酸钠对啮齿动物肠道中滴滴涕吸收影响的比较。

A comparison of the effects of mineral oil, vegetable oil, and sodium sulfate on the intestinal absorption of DDT in rodents.

作者信息

Keller W C, Yeary R A

出版信息

Clin Toxicol. 1980 Apr;16(2):223-31. doi: 10.3109/15563658008989941.

Abstract

The effects of mineral oil, vegetable oil, and sodium sulfate on the intestinal absorption of a highly lipid soluble pesticide, DDT, were compared in the rat. Intestinal absorption was evaluated by measuring recovery of DDT and metabolites in feces and the concentration of DDT in adipose tissue following oral administration of DDT and each agent. Vegetable oil was shown to significantly increase absorption of DDT when compared to all other treatments.

摘要

在大鼠中比较了矿物油、植物油和硫酸钠对一种高脂溶性农药滴滴涕肠道吸收的影响。通过测量口服滴滴涕及每种试剂后粪便中滴滴涕和代谢物的回收率以及脂肪组织中滴滴涕的浓度来评估肠道吸收情况。与所有其他处理相比,植物油被证明能显著增加滴滴涕的吸收。

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