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犬心脏中放射性碘标记的十六碳烯酸（I-HA）与氯化铊201Tl的比较。I-HA用于心肌成像的意义。

A comparison between terminally radioiodinated hexadecenoic acid (I-HA) and 201Tl-thallium chloride in the dog heart. Implications for the use of I-HA for myocardial imaging.

作者信息

Westera G, van der Wall E E, Heidendal G A, van den Bos G C

出版信息

Eur J Nucl Med. 1980 Aug;5(4):339-43. doi: 10.1007/BF00445621.

DOI:10.1007/BF00445621
PMID:7398671
Abstract

The regional myocardial distribution of 131I-16-iodo-9-hexadecenoic acid (131I-HA) and 201Tl-thallium chloride (201TlCl) was determined in normal dogs and after occlusion of a coronary artery. The uptake of 131I-HA was about 20% lower than that of 201TlCl but the ratio 201Tl/131I was the same for the whole myocardium within narrow limits for normal as well as infarcted tissue. The potential of 123I-HA as a radiopharmaceutical for diagnosis of myocardial defects is discussed.

摘要

在正常犬以及冠状动脉闭塞后，测定了131I-16-碘-9-十六碳烯酸（131I-HA）和201Tl-氯化铊（201TlCl）的区域性心肌分布。131I-HA的摄取量比201TlCl低约20%，但对于正常组织和梗死组织，整个心肌的201Tl/131I比值在狭窄范围内是相同的。讨论了123I-HA作为诊断心肌缺损的放射性药物的潜力。

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2
A comparison between terminally radioiodinated hexadecenoic acid (125I-HA) and heptadecanoic acid (131I-H0A) in the dog heart.犬心脏中放射性碘标记的十六碳烯酸（125I-HA）与十七烷酸（131I-H0A）的比较。
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Relationship between the reduction in coronary flow and the appearance of electrocardiographic changes.冠状动脉血流减少与心电图变化出现之间的关系。
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External detection of regional myocardial metabolism with radioiodinated hexadecenoic acid in the dog heart.
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Radioiodinated fatty acids for heart imaging: iodine monochloride addition compared with iodide replacement labeling.
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Experimental basis of myocardial imaging with 123I-labeled hexadecenoic acid.
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Spatial and temporal heterogeneity of left ventricular perfusion in awake dogs.清醒犬左心室灌注的时空异质性
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