Principles of ethics in animal experimentation.

The attached principles were compiled at Talloires by the ad hoc international group formed as a result of the International Symposium on 'The Laboratory Animal in the Service of Mankind' held in Lyon (France) in September 1978 in honor of Claude BERNARD on the 100th anniversary of his death. These are in effect a reaffirmation of principles long in practice in many countries. An effort has been made to bring these together in a manner which would be most clearly understood and accepted on an international basis.