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从甲基胆蒽诱导肿瘤上表达的外来H-2k抗原中分离肿瘤相关移植抗原(TATA)。

Separation of the tumor-associated transplantation antigen (TATA) from the alien H-2k antigens expressed on a methylcholanthrene-induced tumor.

作者信息

Rogers M J, Law L W, Pierotti M A, Parmiani G

出版信息

Int J Cancer. 1980 Jan 15;25(1):105-9. doi: 10.1002/ijc.2910250114.

DOI:10.1002/ijc.2910250114
PMID:7399738
Abstract

The tumnor-associated transplantation antigen (TATA), alien H-2k antigens and normal H-2d antigens expressed on a methylcholanthrene-induced tumor were monitored during gel filtration and lectin affinity chromatography of detergent-solubilized tumor-cell membranes. TATA was resolved from both the normal and alien H-2 antigens by these techniques. The relationship between histocompatibility antigens and TATA is discussed.

摘要

在对去污剂溶解的肿瘤细胞膜进行凝胶过滤和凝集素亲和层析过程中,监测了甲基胆蒽诱导肿瘤上表达的肿瘤相关移植抗原(TATA)、外来H-2k抗原和正常H-2d抗原。通过这些技术,TATA与正常和外来H-2抗原得以分离。本文讨论了组织相容性抗原与TATA之间的关系。

相似文献

1
Separation of the tumor-associated transplantation antigen (TATA) from the alien H-2k antigens expressed on a methylcholanthrene-induced tumor.从甲基胆蒽诱导肿瘤上表达的外来H-2k抗原中分离肿瘤相关移植抗原(TATA)。
Int J Cancer. 1980 Jan 15;25(1):105-9. doi: 10.1002/ijc.2910250114.
2
Biochemical characterization of alien H-2 antigens expressed on a methylcholanthrene-induced tumor.甲基胆蒽诱导肿瘤上表达的外来H-2抗原的生化特性
Proc Natl Acad Sci U S A. 1979 Mar;76(3):1415-9. doi: 10.1073/pnas.76.3.1415.
3
Alien H-2 antigens (H-2k) appearing on a methylcholanthrene-induced tumor (H-2d): biochemical characterization.出现在甲基胆蒽诱导肿瘤(H-2d)上的外来H-2抗原(H-2k):生化特性
Transplant Proc. 1980 Mar;12(1):38-45.
4
Tumor rejection activity of antigens isolated from the membranes of a methylcholanthrene-induced sarcoma, C-1, bearing alien H-2 antigens.从携带外来H-2抗原的甲基胆蒽诱导肉瘤C-1的细胞膜中分离出的抗原的肿瘤排斥活性。
Transplant Proc. 1980 Mar;12(1):46-9.
5
Alien H-2 antigens on a chemically induced fibrosarcoma: further evidence in crude membrane and soluble extracts of the tumor.化学诱导纤维肉瘤上的异体H-2抗原:肿瘤粗膜提取物和可溶性提取物中的进一步证据
Tumori. 1979 Jun 30;65(3):295-308. doi: 10.1177/030089167906500304.
6
Biological and biochemical properties of Nonidet P40-solubilized and partially purified tumor-specific antigens of the transplantation type from plasma membranes of a methylcholanthrene-induced sarcoma.由甲基胆蒽诱导的肉瘤细胞膜中移植型非离子型去污剂P40增溶并部分纯化的肿瘤特异性抗原的生物学和生物化学特性
Cancer Res. 1977 Sep;37(9):3406-13.
7
Partial purification of tumour-specific transplantation antigens from methylcholanthrene-induced murine sarcomas by immobilized lectins.用固定化凝集素对甲基胆蒽诱导的小鼠肉瘤中的肿瘤特异性移植抗原进行部分纯化。
Br J Cancer. 1979 Dec;40(6):831-8. doi: 10.1038/bjc.1979.273.
8
Expression of alien minor histocompatibility antigens distinct from tumor-specific transplantation antigen on a murine fibrosarcoma.在小鼠纤维肉瘤上表达与肿瘤特异性移植抗原不同的外来次要组织相容性抗原。
Int J Cancer. 1980 Oct 15;26(4):461-5. doi: 10.1002/ijc.2910260411.
9
Biologic and biochemical properties of detergent-solubilized tumor-specific transplantation antigen from a simian virus 40-induced neoplasm: brief communication.来自猿猴病毒40诱导肿瘤的去污剂增溶肿瘤特异性移植抗原的生物学和生化特性:简报
J Natl Cancer Inst. 1977 Oct;59(4):1331-3. doi: 10.1093/jnci/59.4.1331.
10
Immunogenicity of H-2 positive and H-2 negative clones of a mouse tumour, GR9.小鼠肿瘤GR9的H-2阳性和H-2阴性克隆的免疫原性
J Immunogenet. 1986 Apr-Jun;13(2-3):159-67. doi: 10.1111/j.1744-313x.1986.tb01097.x.

引用本文的文献

1
Resistance of the Meth A sarcoma-associated rejection antigen to inactivation with glutaraldehyde.甲基肉瘤相关排斥抗原对戊二醛失活的抗性。
Br J Cancer. 1981 Oct;44(4):584-7. doi: 10.1038/bjc.1981.230.
2
Noncytolytic extraction of cell surface antigens using butanol.使用丁醇对细胞表面抗原进行非溶细胞提取。
Cancer Metastasis Rev. 1985;4(3):209-19. doi: 10.1007/BF00048096.
3
The effect of purification on the immunogenicity of tumor-specific transplantation antigens.纯化对肿瘤特异性移植抗原免疫原性的影响。
Cancer Immunol Immunother. 1985;19(1):22-7. doi: 10.1007/BF00199307.