Puccetti P, Santoni A, Riccardi C, Herberman R B
Int J Cancer. 1980 Jan 15;25(1):153-8. doi: 10.1002/ijc.2910250121.
Cells with in vitro cytotoxicity against tumor targets in a short-term 51Cr release assay have been recovered from the lungs of mice that were either untreated or injected with biological or synthetic agents 1--3 days earlier. The cytotoxic effector cells were non-adherent, non-phagocytgic and shared many characteristics with splenic natural killer (NK) cells. This finding is discussed with particular regard to our previous observations on the rapid in vivo elimination from the lungs of intravenously injected, radiolabelled tumor cells.
在短期⁵¹Cr释放试验中，对肿瘤靶标具有体外细胞毒性的细胞，已从未处理或在1至3天前注射了生物或合成制剂的小鼠肺中分离出来。细胞毒性效应细胞不黏附、不吞噬，并且与脾自然杀伤（NK）细胞具有许多共同特征。结合我们之前关于静脉注射放射性标记肿瘤细胞在肺内快速体内清除的观察结果，对这一发现进行了讨论。
