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人类妊娠血清和羊水中的免疫复合物。

Immune complexes in the sera and amniotic fluids of human pregnancy.

作者信息

Pachì A, D'Amelio R, Palmisano L, Bilotta P, Milano C F, De Gado F, Aiuti F

出版信息

J Perinat Med. 1980;8(2):109-11. doi: 10.1515/jpme.1980.8.2.109.

DOI:10.1515/jpme.1980.8.2.109
PMID:7400917
Abstract

The polyethylene-glicol (P.E.G.) precipitation assay was used to examine the sera of 91 pregnant women, 30 with normal pregnancies, 16 with EPH-Gestosis, 20 with pregnancy complicated by diabetes and 25 with case histories of recurrent abortions, in order to find evidence of eventual circulating immune complexes (C.I.C.). We also examined 30 amniotic fluids from normal pregnant women and 6 from pregnant women with diabetes. Several sera and all amniotic fluids were also examined by rheumatoid factor (RF) - inhibition test. C.I.C. were not discovered in the normal pregnant women neither in their sera nor in their amniotic fluids, while they were found in the following cases: in 8 patients with EPH-Gestosis (50%), in 8 with diabetes (40%) and in 3 with anamnesis positive for recurrent abortions (12%). The 6 amniotic fluid samples from women with diabetes were all negative. We were only able to examine 11 of the 19 positive cases from 4 days to 5 months after delivery and C.I.C. were absent in the sera of all the patients.

摘要

采用聚乙二醇(P.E.G.)沉淀试验检测了91名孕妇的血清,其中30名妊娠正常,16名患妊娠高血压综合征,20名妊娠合并糖尿病,25名有习惯性流产病史,以寻找循环免疫复合物(C.I.C.)存在的证据。我们还检测了30名正常孕妇和6名糖尿病孕妇的羊水。部分血清和所有羊水还通过类风湿因子(RF)抑制试验进行了检测。正常孕妇的血清和羊水中均未发现C.I.C.,而在以下病例中发现了C.I.C.:8名妊娠高血压综合征患者(50%),8名糖尿病患者(40%),3名习惯性流产病史呈阳性的患者(12%)。6名糖尿病孕妇的羊水样本均为阴性。分娩后4天至5个月,我们仅对19例阳性病例中的11例进行了检测,所有患者血清中均未发现C.I.C.。

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Immune complexes in the sera and amniotic fluids of human pregnancy.人类妊娠血清和羊水中的免疫复合物。
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