组织中乙醇和乙醛的气相色谱测定法
Gas-liquid chromatographic determination of ethanol and acetaldehyde in tissues.
作者信息
Brien J F, Hoover D J
出版信息
J Pharmacol Methods. 1980 Aug;4(1):51-8. doi: 10.1016/0160-5402(80)90043-1.
PMID:7401649
Abstract
A gas-liquid chromatographic procedure, involving head-space analysis, is described for the determination of ethanol and acetaldehyde in the blood, liver, heart, and brain of the rat. The lower limit of sensitivity of the assay is 0.05 mg/ml (mg/g) ethanol and 0.25 micrograms/ml (micrograms/g) acetaldehyde. The coefficient of variation of the method is less than 6% for ethanol and less than 9% for acetaldehyde. This procedure has been used in the investigation of the calcium carbimide-ethanol interaction.
摘要
本文描述了一种采用顶空分析的气液色谱法，用于测定大鼠血液、肝脏、心脏和大脑中的乙醇和乙醛。该测定方法的灵敏度下限为0.05毫克/毫升（毫克/克）乙醇和0.25微克/毫升（微克/克）乙醛。该方法的变异系数对于乙醇小于6%，对于乙醛小于9%。此方法已用于研究卡巴咪嗪 - 乙醇的相互作用。
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