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小鼠前脑不同区域神经脂肥大细胞的形态学寿命研究。

A morphological lifespan study of neurolipomastocytes in various regions of the mouse forebrain.

作者信息

Sturrock R R

出版信息

Neuropathol Appl Neurobiol. 1980 May-Jun;6(3):211-19. doi: 10.1111/j.1365-2990.1980.tb00291.x.

DOI:10.1111/j.1365-2990.1980.tb00291.x
PMID:7402437
Abstract

The neostriatum, indusium griseum and anterior commissure of the mouse brain were examined by semithin light microscopy and electron microscopy in an attempt to identify and follow the development of the cells named neurolipomastocytes by Ibrahim et al. (1979). These cells were first seen at 5 days post natum in the indusium griseum and in the leptomeninges adjacent to it. Neurolipomastocptes were always associated with arterioles or venules almost invariably at the site of vessel branching. Their major feature was the presence of round osmiophilic granules. In older animals their cytoplasm contained large quantities of foamy vesicles. This foamy cytoplasm was restricted to neurolipomastocytes and was not a feature of ageing capillary pericytes which showed little morphological evidence of ageing apart from the occasional lipofuscin body.

摘要

为了识别并追踪Ibrahim等人(1979年)命名的神经脂肥大细胞的发育过程,利用半薄光学显微镜和电子显微镜对小鼠脑的新纹状体、灰被和前连合进行了检查。这些细胞最早在出生后5天出现在灰被及其相邻的软脑膜中。神经脂肥大细胞几乎总是与小动脉或小静脉相关联,且几乎都位于血管分支处。它们的主要特征是存在圆形嗜锇颗粒。在年龄较大的动物中,其细胞质含有大量泡沫状小泡。这种泡沫状细胞质仅限于神经脂肥大细胞,并非衰老的毛细血管周细胞的特征,除了偶尔出现的脂褐素小体之外,衰老的毛细血管周细胞几乎没有形态学上的衰老证据。

相似文献

1
A morphological lifespan study of neurolipomastocytes in various regions of the mouse forebrain.小鼠前脑不同区域神经脂肥大细胞的形态学寿命研究。
Neuropathol Appl Neurobiol. 1980 May-Jun;6(3):211-19. doi: 10.1111/j.1365-2990.1980.tb00291.x.
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A comparative quantitative and morphological study of ageing in the mouse neostriatum, indusium griseum and anterior commissure.小鼠新纹状体、灰被和前连合衰老的比较定量与形态学研究。
Neuropathol Appl Neurobiol. 1980 Jan-Feb;6(1):51-68. doi: 10.1111/j.1365-2990.1980.tb00204.x.
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A quantitative lifespan study of changes in cell number, cell division and cell death in various regions of the mouse forebrain.一项关于小鼠前脑不同区域细胞数量、细胞分裂和细胞死亡变化的定量寿命研究。
Neuropathol Appl Neurobiol. 1979 Nov-Dec;5(6):433-56. doi: 10.1111/j.1365-2990.1979.tb00642.x.
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A morphological study of the neostriatum of aged mice with particular reference to neuroglia.老年小鼠新纹状体的形态学研究,特别涉及神经胶质细胞。
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Development of the indusium griseum. II. A semithin light microscopic and electron microscopic study.灰被的发育。II. 半薄切片光镜和电镜研究。
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引用本文的文献

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Evidence for the possible function of the fluorescent granular perithelial cells in brain as scavengers of high-molecular-weight waste products.脑内荧光颗粒周皮细胞可能作为高分子量废物清除剂的功能证据。
Experientia. 1984 Apr 15;40(4):399-402. doi: 10.1007/BF01952574.
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Development of granular pial cells and granular perithelial cells in the spinal cords of mouse and rabbit.小鼠和兔脊髓中颗粒状软膜细胞和颗粒状被膜周细胞的发育。
J Anat. 1987 Aug;153:113-22.
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Interactions of mast cells with the nervous system--recent advances.肥大细胞与神经系统的相互作用——最新进展
Neurochem Res. 1992 Sep;17(9):939-51. doi: 10.1007/BF00993271.